Endocrine Abstracts

Premature Ovarian Insufficiency (POI) is defined as impairement of ovarian function in women under 40 years, with a incidence between 1-4% in women of reproductive age. Among the major identified causes of Premature Ovarian Insufficiency, genetic factors related with X-chromosome are widely described. However, autosome defects are less common found and are related generally with genetic mutations instead of structural abnormalities of them. Thefor, we report a relevant case of...

Introduction: Graves’ and Hashimoto’s diseases are considered two extremes of the same autoimmune thyroid disease. Spontaneous conversion from hypothyroidism to hyperthyroidism is uncommon. On the other hand, Graves’ disease typically improves during pregnancy and worsens after delivery. We describe a patient with an unusual course of thyroid disease during pregnancy.Case report: An 33-year-old woman, with a two-year history of hypothyroid...

Introduction: The thyroid-related quality-of-life patient-reported outcome ThyPRO questionnaire is the most widely used tool for measuring health-related quality of life (QoL) in patients with benign thyroid diseases. The aim of this study was to adapt and validate a Spanish version of the ThyPRO.Methods: The ThyPRO consists of 85 items, grouped in 13 scales and one single QoL item. Scales cover physical and mental symptoms, well-being and function, soci...